Não podemos nos esquecer de que o uso de GH rDNA é para o crescimento estatural em humanos com DGH em virtude dos benefícios inúmeros que serão agregados ao paciente seja criança, infantil-juvenil-pré-púbere ou púbere, incluindo com outros objetivos em adultos e nesses casos os riscos serão desprezíveis e é válido em qualquer fase do desenvolvimento humano.
WANT TO GROW: INTERDIGITATION ENDOCRINOLOGY BETWEN PHYSIOLOGY WITH OTHER PROCESSES OF SPECIALTIES.
TO GROW HEALTHY: SOMETIMES STAIN THE ROLE OF HORMONES. E.G., THE HORMONES PLAY AN IMPORTANT ROLE IN MAINTAINING BLOOD PRESSURE, VOLUME INTRAVASCULAR, AND PERIPHERAL RESISTANCE OF CARDIOVASCULAR SYSTEM. VASOACTIVE SUBSTANCES, SUCH AS CATECHOLAMINES, ANGIOTENSIN II, ENDOTHELIN AND NITRIC OXIDE ARE INVOLVED IN CHANGES IN DYNAMIC VASCULAR TONE ADDITION TO YOUR MULTIPLE FUNCTIONS IN OTHER FABRICS. PHYSIOLOGY-ENDOCRINOLOGY-NEUROENDOCRINOLOGY-GENETICS-ENDOCRINE-PEDIATRICS (SUBDIVISION OF ENDOCRINOLOGY): DR. JOÃO SANTOS CAIO JR. ET DRA. HENRIQUETA VERLANGIERI CAIO.
Not infrequently patients and medical professionals present some stigmas regarding hormones, probably this observation comes from the 50s with the discovery of therapeutic cortisone at that time was like opening a Pandora's box, which led to widespread misconception, perhaps for lack of information or even the complexity of the issue, although it is recognized that as a clinical doctor of any other specialty endocrinology and neuroendocrinology and it is almost impossible for us to get knowledge about all the advanced research that has involved endocrinology, beyond the need for make progress in knowledge that are not so clear. This situation suggests that there is undoubtedly a need for exchange of ideas among professionals, attendance at conferences and reading journals and books and accompanying research, it is clear that this passage means and redundant. The heart is the main source of atrial natriuretic peptide, which acts on the classical endocrine fashion to induce natriuresis at a distant target organ (the kidney). Erythropoietin, a traditional hormone circulating is made in the kidney and stimulates erythropoiesis in the bone marrow.
The kidney is also integrally involved in the renin angiotensin system and is the main target of several hormones, including parathyroid hormone (PTH), mineralocorticoid and vasopressin. The gastrointestinal tract produces a surprising number of peptide hormones such as cholecystokinin, ghrelin, gastrin, secretin, and vasoactive intestinal peptide, among many others. Adipose tissue produces leptin, which acts centrally to control appetite. Hormones such as inhibin, leptin and ghrelin are discovered; they become integrated into the science and practice of medicine and based on their functional roles rather than the tissue of origin. The characterization of hormone receptors often reveals unexpected relationships to non-endocrine factors in disciplines. The GH and leptin receptor, e. g., are members of the cytokine receptor family. The G-protein coupled receptors (GPCR), which mediate the actions of many hormones peptides are used in numerous physiological processes, including vision, olfaction and neurotransmission. It sure humans with severe pathologies with morbid obesity that has few alternatives to resolve a condition that will inevitably lethal outcome, although we do not know everything that can happen in the long term, much less substances that are extremely important and are not clear, has few options to equate pathology as disastrous, but what differs on whether or not a radical act is the guidance of a well made professional presenting a perfect and accurate indication. Let us not forget that the height growth is indicated for humans with DGH because of the numerous benefits that will be added to the patient is a child, child-youth-prepubescent or pubescent, including with other goals in adults and in these cases the risks will be negligible and is valid at any stage of human development.
Dr. João Santos Caio Jr.
Endocrinologia – Neuroendocrinologista
CRM 20611
Dra. Henriqueta V. Caio
Endocrinologista – Medicina Interna
CRM 28930
Como saber mais:
1. Crianças menores de 3 anos devem ser medidas em uma plataforma horizontal sobre uma maca que contém três componentes essenciais: um critério ligado, um Headplate fixa, e uma platina móvel... http://hormoniocrescimentoadultos.blogspot.com
2. A medida da altura imprecisa pode resultar em falha na detecção de distúrbios do crescimento ou encaminhamentos inadequados para crianças com crescimento normal...
http://longevidadefutura.blogspot.com
3. Traçar as medições em um gráfico de crescimento é essencial para documentar e monitorar a progressão longitudinal do tamanho de uma criança (ou seja, peso e altura em relação aos dados normativos estabelecidos da criança)...
http://imcobesidade.blogspot.com
AUTORIZADO O USO DOS DIREITOS AUTORAIS COM CITAÇÃO
DOS AUTORES PROSPECTIVOS ET REFERÊNCIA BIBLIOGRÁFICA.
Referências Bibliográficas:
Caio Jr, João Santos, Dr.; Endocrinologista, Neuroendocrinologista, Caio,H. V., Dra. Endocrinologista, Medicina Interna – Van Der Häägen Brazil, São Paulo, Brasil; DeGroot LJ, Jameson JL (eds): Endocrinology, 5th ed. Philadelphia, Elsevier, 2006. Hammes Aet al: Role of endocytosis in cellular uptake of sex steroids. Cell 122:751, 2005. Leo CP et al: Hormonal genomics. Endocr Rev 23:369, 2002. Marx SJ, Simonds WF: Hereditary hormone excess: Genes, molecular pathways, and syndromes. Endocr Rev 26:615, 2005. Smith CL et al: Coregulator function: A key to understanding tissue specificity of selective receptor modulators. Endocr Rev 25:45, 2004. Weinstein LS et al: Minireview: GNAS: Normal and abnormal functions. Endocrinology 145:5459, 2004.
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João Santos Caio Jr
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